Spring 2021 Lecture Materials
Unit 4: Macromolecular structure and function
May 11
Lecture 1: Introduction to Protein Structure [slides]
Installing PyMol:
DOWNLOAD URL: https://pymol.org/ep USERNAME: jun2021 PASSWORD: betabarrel
Installing PyRosetta:
DOWNLOAD URL: http://www.pyrosetta.org/dow USERNAME: teaching PASSWORD: scorefunction
Additional reading: [PyMol] [PyRosetta]
Homework #7: Due 11:59pm Friday May 21 [hw#7]
May 13
Lecture 2: Protein Structure Modeling 1: Forcefields [slides]
PyRosetta Demo #1: [ipynb][demo1.py]
May 18
Lecture 3: Protein Structure Modeling 2: Structure Prediction and Protein Design [slides]
PyRosetta Demo #2: [ipynb][demo2.py]
Homework #8: Due 11:59pm Friday May 28 [hw#8][hw#8 files]
Further Reading: [Deep learning for protein structure prediction]
May 20
Lecture 4: Nucleic Acid Structure [slides]