Model-building and refinement into cryoEM density
Our cryoEM model-building and refinement tools are included as part of the Rosetta software package.
2019 CryoEM model metrics challenge
Our lab participated in this challenge in May 2019.
You may also download sections individually:
- Part 1: Introduction to Rosetta for cryoEM [pdf][tgz]
- Part 2: Fragment-based structure refinement [pdf][tgz]
- Part 3: Model rebuilding using RosettaCM [pdf][tgz]
- Part 4: De novo EM-guided structure determination [pdf][tgz]
- Part 5: Rebuilding long protein segments with RosettaES [pdf][tgz]
Slides from a workshop at Karolinska Institutet, August 2018
- Lecture 1 – Intro to Rosetta for cryoEM modelling [pdf]
Slides from the Jülich “Hands-on” Workshop on Computational Biophysics, August 2016